Research paper on congestive heart failure

Keywords: biomarker, heart failure, ICD 10, readmission, utilization 1. This in turn contributes to the elevated pro-inflammatory response reported in patients with HF. Finding a new balance certainly requires a thorough overview, with delicate attention to both true insights and practical feasibility.

A recent review by Simons et al. Clinically, it is typically classified into two major types based on the functional status of heart: heart failure with preserved ejection fraction HFpEF and heart failure with reduced ejection fraction HFrEF. The most common cause for HF is reduced left ventricular myocardial function; however, dysfunction of the pericardium, myocardium, endocardium, heart valves or great vessels alone or in combination is also associated with HF.

Heart failure journal

Recent research has uncovered the microvascular dysfunction and subsequent decrease in O2 supply or mismatch with the O2 supply vs. A look at current cardiac research reveals an exciting, and at the same time somewhat turbulent field. Similarly, the percentage of in-hospital HF-related deaths declined from The study by Dhakal et al is focused on the problem of renal dysfunction in patients with heart failure. In contrast, the relationship of end-systolic volume ESV to EDV emerges as an insightful framework, incorporating both systolic and diastolic properties. In a study involving nearly 7, men and women, Johns Hopkins researchers were able to discover the underlying reason that African-Americans are known to develop heart disease more than any other race. A simple blood test can determine which patients will fare better after hospital discharge. Among their recent findings: African-Americans are at increased risk of congestive heart failure. Some of the major pathogenic mechanisms leading to HF are increased hemodynamic overload, ischemia-related dysfunction, ventricular remodeling, excessive neuro-humoral stimulation, abnormal myocyte calcium cycling, excessive or inadequate proliferation of the extracellular matrix, accelerated apoptosis and genetic mutations [ 1 ]. The body tries to compensate in different ways. In the USA itself, about more than three million physician visits per year have been accounted for patients with HF as the primary health issue. There is indeed a slight decrease in HF-related mortality from to Also steer clear of secondhand smoke. High-output failure is an uncommon disorder characterized by an elevated resting cardiac index of greater than 2.

Unfortunately, these numbers are on a gradual increase due to the on-going prevalence of HF with increasing age. Multiple biomarkers have been classified depending on their putative functional impact on cardiac myocytes and the resulting pathophysiological changes in patients with HF and include a myocyte stretch biomarkers; b myocyte necrosis biomarkers; c systemic inflammation biomarkers; d oxidative stress biomarkers; e extracellular matrix turnover biomarkers; f neuro-hormone biomarkers; and g biomarkers of extra-cardiac processes, such as renal function.

Weighing yourself daily is one of the easiest ways to track fluid retention, indicated by a sudden gain. The work of Singh et al underlines the importance of coronary artery disease in the study of ischemic left LV dysfunction and heart failure.

congestive heart failure articles 2017

This occurs as a result of ineffective blood volume and pressure, which stimulate the sympathetic nervous system and renin-angiotensin-aldosterone system RAAScausing the release of antidiuretic hormone ADHwhich all together ultimately lead to ventricular enlargement, negative ventricular remodeling and HF.

Among their recent findings: African-Americans are at increased risk of congestive heart failure.

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Congestive Heart Failure: Prevention, Treatment and Research